DETAILED NOTES ON LIMITED EDITION EXCLUSIVE LSD CRYSTAL)

Within the LSD-bound crystal construction, the aspect chain of the lid residue L209EL2 forms considerable hydrophobic contacts with equally LSD and surrounding residues in TMs III, IV, and V (Determine 4C). In the event the lid moved aside to show the binding pocket in simulation, various of these contacts broke. We Hence hypothesized that L209EL2